019 – INCaSe + HA

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Background:

INCaSe panels include an Inflammation Assessment, Cancer Risk Assessment and Vitamin D test.  The name INCaSe has been retired, however the elements are still available for ordering.  The most similar panel is the 105 – Canine Essential Wellness + CRA:

Canine Essential Wellness + CRA includes an inflammation assessment with C-Reactive Protein (CRP) and two of the most important essential vitamins: Vitamin D (25OHD) and Cobalamin (Vitamin B12).  Additionally, screening for early signs of cancer is done using TK1 providing the Cancer Risk Assessment (CRA).  CRA is a way to see the risk of a major cancer event in the coming 4-6 months.  Early detection leads to early intervention, more options, and better outcomes.

Apparently healthy dogs should not have systemic inflammation.  When present, source of inflammation should be identified and resolved if possible before it becomes chronic.  Chronic inflammation leads to the development of serious diseases including cancer.  Detect occult disease in the otherwise healthy looking dog using the single most effective test for overall health: CRP.

Additionally, screening for early signs of Degenerative Joint Diseases like Osteoarthritis (OA) is done using Hyaluronic Acid (HA).  Joint Disease is typically viewed as an old-dog disease, however the degeneration of joints can start early in life and not present clinically until later.  Using HA to detect when that degeneration begins, allows earlier intervention and more options to slow or stop the progression of joint disease

Clinical Applications:

  1. General Wellness (annual or biannual screening)
  2. Apparently Healthy dogs
  3. Dogs at high risk of inflammatory diseases
  4. Dogs at risk of cancer
  5. Pet Parents wanting to be proactive in detecting & managing disease

Recommendations:

Health screening using a sensitive inflammatory marker, CRP, should begin once the dog reaches an adult stage.  Annual testing while apparently healthy is the minimum recommended interval with bi-annual screening being the most effective way to detect the presence of occult disease.

Dogs at risk of cancer benefit from bi-annual testing of CRA.  For best results, CRA should be performed every 4 months.

Evaluating essential vitamin levels should start once the dog or cat reaches adult stages and establishes their adult diet.  Once diet has been stable for 3 months, test baseline vitamins and correct any insufficiencies with supplementation, or consider a diet change if values are considerably low.  VDI provides patient-specific dosing guidelines for both Vitamin D and B12.  Recheck intervals are every year once sufficient unless diet or health changes occur.

Category:

Additional information

Species

Canine

Patient Status

Apparently Healthy

Test

C-Reactive Protein (CRP), Cancer Risk Assessment (CRA), Hyaluronic Acid (HA), Thymidine Kinase type 1 (TK1), Vitamin D (VitD)

Specimen Type

Serum (Frozen or Dry)

Dry Serum Volume

1 Well

Fasting

Not Required