301 – Osteoarthritis Panel

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Degenerative joint disease (DJD) is a common, age-related breakdown of the joint.  Osteoarthritis (OA) is the most commonly diagnosed DJD in both human and veterinary medicine and affects 20% of dogs older than one year and a stunning 80% in dogs greater than 8 years.  Hyaluronic Acid (HA) is a marker of DJD and will increase and subsequently decrease with disease advancement.  Some DJD is inflammatory and may cause a rise in inflammatory marker CRP/HPT (e.g. IMPA).  In advanced DJD, deterioration of the joint capsule and increased mechanical damage will lead to increases in inflammatory marker CRP/HPT.

The Osteoarthritis Panel is designed to detect and monitor changes in the degenerative joint marker Hyaluronic Acid and inflammatory marker CRP/HPT before, during, and after therapy, to manage patients with osteoarthritis or other degenerative joint diseases.  Learn more. 

Clinical Applications:

  1. Patients suspected of OA, IVDD, IMPA, or other joint damage
  2. High Risk breeds that may be prone to early onset degenerative joint disease
  3. Patients with confirmed DJD undergoing therapy


The Osteoarthritis Panel should be performed prior to administration of steroids, chemo, NSAIDs or other therapy whenever possible.  VDI can interpret results around the presence of therapy, but please be sure to indicate on the Test Requisition Form any medications at the time of draw.

Contact VDI for consultation on any case to determine the best repeat test window.


Additional information


Canine, Feline

Patient Status

Acutely Ill, Apparently Healthy


C-Reactive Protein (CRP), Hyaluronic Acid (HA)

Specimen Type

Serum (Frozen or Dry)

Dry Serum Volume

1 Well


Not Required