126 – Essential Vitamins 1 + HA

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Essential Vitamins 1 + HA panel includes Vitamin D (25OHD) and Cobalamin (Vitamin B12) – two essential nutrients that are only obtained through diet, and Hyaluronic Acid (HA) – a marker of degenerative joint disease.  Vitamin D, the most important hormone in the body, is responsible for supporting the innate immune system and has a role in disease prevention and management.  Sufficient levels are anti-inflammatory, anti-proliferative, and pro-immunity.  Cobalamin is chiefly response for DNA production as a critical cofactor.  Learn more about VitD and B12 here.   VDI provides patient-specific dosing guidelines for Vitamin D and B12.

Joint Disease is typically viewed as an old-dog disease, however the degeneration of joints can start early in life and not present clinically until later.  Using HA to detect when that degeneration begins, allows earlier intervention and more options to slow or stop the progression of joint disease.   Learn more. 

Clinical Applications:

  1. Diet Changes
  2. Gastrointestinal Disease
  3. Inflammatory Disease
  4. Cancer Patients
  5. General Wellness – preventative
  6. PLE Patients
  7. Patients on NSAIDs or Corticosteroids


Evaluating essential vitamin levels should start once the dog or cat reaches adult stages and establishes their adult diet.  Once diet has been stable for 3 months, test baseline vitamins and correct any insufficiencies with supplementation, or consider a diet change if values are considerably low.   Recheck intervals are every year once sufficient unless diet or health changes occur.

Dogs at risk of Joint Disease benefit from bi-annual testing of Hyaluronic Acid (HA).


Additional information


Canine, Feline

Patient Status

Acutely Ill, Apparently Healthy, Suspected Cancer, Suspected GI Disease


Hyaluronic Acid (HA), Vitamin B12 (B12), Vitamin D (VitD)

Specimen Type

Serum (Frozen or Dry)

Dry Serum Volume

1 Well


Recommended: 8hr