138 – Essential Wellness 2 + CRA

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Background:

Essential Wellness 2 + CRA includes an inflammation assessment with C-Reactive Protein (CRP) or Haptoglobin (HPT) and Essential Vitamins 2 panel which includes: Vitamin D (25OHD), Cobalamin (Vitamin B12), Folate (Fol) and  Magnesium (Mg). Apparently healthy animals should not have systemic inflammation.  When present, source of inflammation should be identified and resolved if possible before it becomes chronic.  Chronic inflammation leads to the development of serious diseases including cancer.  Detect occult disease in the otherwise healthy looking pet using the single most effective test for overall health: CRP (dog) or HPT (cat).

Additionally, screening for early signs of cancer is done using TK1 providing the Cancer Risk Assessment (CRA).  CRA is a way to see the risk of a major cancer event in the coming 4-6 months.  Early detection leads to early intervention, more options, and better outcomes.

Vitamin D, the most important hormone in the body, is responsible for supporting the innate immune system and has a role in disease prevention and management.  Sufficient levels are anti-inflammatory, anti-proliferative, and pro-immunity. Cobalamin and folate are chiefly response for DNA/RNA production as critical cofactors. Magnesium is a cofactor in hundreds of enzymatic processes, and when low those reactions are less efficient.  Learn more.   VDI provides patient-specific dosing guidelines for both Vitamin D, B12, and Magnesium.

Folate is an essential nutrient involved in numerous biological pathways, acting as a cofactor to ensure they run efficiently and effectively.

Clinical Applications:

  1. General Wellness (annual or biannual screening)
  2. Apparently Healthy pets
  3. Pets at high risk of inflammatory diseases
  4. Pet Parents wanting to be proactive in detecting & managing disease

Recommendations:

Health screening using a sensitive inflammatory marker, CRP/HPT, should begin once the pet reaches an adult stage.  Annual testing while apparently healthy is the minimum recommended interval with bi-annual screening being the most effective way to detect the presence of occult disease.

Evaluating essential vitamin levels should start once the dog or cat reaches adult stages and establishes their adult diet.  Once diet has been stable for 3 months, test baseline vitamins and correct any insufficiencies with supplementation, or consider a diet change if values are considerably low.  VDI provides patient-specific dosing guidelines for Vitamin D, B12 and Mg.  Recheck intervals are every year once sufficient unless diet or health changes occur.

Category:

Additional information

Species

Canine, Feline

Patient Status

Apparently Healthy

Test

C-Reactive Protein (CRP) or Haptoglobin (HPT), Cancer Risk Assessment (CRA), Folate (Fol), Magnesium (Mg), Thymidine Kinase type 1 (TK1), Vitamin B12 (B12), Vitamin D (VitD)

Specimen Type

Serum (Frozen or Dry)

Dry Serum Volume

2 Wells

Fasting

Recommended: 8hr