306 – Cancer Panel + Calcemia Panel ❄
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*This panel may be listed as 306b – indicating that the Neoplasia Index is modified for specific use in Lymphoma to improve sensitivity and specificity for that application. All other features remain the same.
The term “hypercalcemia of malignancy” is routinely used when calcium is elevated and PTH is below normal, and for good reason— this situation is often a result of malignant neoplasia, particularly lymphoma, anal sac adenocarcinoma, or multiple myeloma. However, many other diseases can fall into this category such as granulomatous disease, hyperthyroidism, vitamin D intoxication, and Addison’s disease.
Cancer Panel + Calcemia Panel is a combination that determines if the cause of hypercalcemia is cancer. Often times, this panel is performed in a serial way:
Step 1: Calcemia Panel to determine if the hypercalcemia falls into the hypercalcemia of malignancy range (High Ca, Low PTH).
Step 2: Cancer Panel to determine if cancer is present, and the possible source of elevated calcium.