306 – Cancer Panel + Calcemia Panel

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*This panel may be listed as 306b – indicating that the Neoplasia Index is modified for specific use in Lymphoma to improve sensitivity and specificity for that application.  All other features remain the same.

Background:

The term “hypercalcemia of malignancy” is routinely used when calcium is elevated and PTH is below normal, and for good reason— this situation is often a result of malignant neoplasia, particularly lymphoma, anal sac adenocarcinoma, or multiple myeloma.  However, many other diseases can fall into this category such as granulomatous disease, hyperthyroidism, vitamin D intoxication, and Addison’s disease.

Cancer Panel + Calcemia Panel is a combination that determines if the cause of hypercalcemia is cancer.  Often times, this panel is performed in a serial way:

Step 1: Calcemia Panel to determine if the hypercalcemia falls into the hypercalcemia of malignancy range (High Ca, Low PTH).

Step 2: Cancer Panel to determine if cancer is present, and the possible source of elevated calcium.

 

 

 

Category:

Additional information

Species

Canine, Feline

Patient Status

Acutely Ill, Suspected Cancer

Test

C-Reactive Protein (CRP), Haptoglobin (HPT), Neoplasia Index (NI), Parathyroid Hormone 1-84 (PTH), Thymidine Kinase type 1 (TK1), Total Calcium (tCa), Vitamin D (VitD)

Specimen Type

Serum (Frozen or Dry)

Dry Serum Volume

3 Wells

Fasting

Not Required