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Minimum Frozen Serum Requirement: 1.5mL
*This panel may be listed as 306b – indicating that the Neoplasia Index is modified for specific use in Lymphoma to improve sensitivity and specificity for that application. All other features remain the same.
Background:
The term “hypercalcemia of malignancy” is routinely used when calcium is elevated and PTH is below normal, and for good reason— this situation is often a result of malignant neoplasia, particularly lymphoma, anal sac adenocarcinoma, or multiple myeloma. However, many other diseases can fall into this category such as granulomatous disease, hyperthyroidism, vitamin D intoxication, and Addison’s disease.
Cancer Panel + Calcemia Panel is a combination that determines if the cause of hypercalcemia is cancer. Often times, this panel is performed in a serial way:
Step 1: Calcemia Panel to determine if the hypercalcemia falls into the hypercalcemia of malignancy range (High Ca, Low PTH).
Step 2: Cancer Panel to determine if cancer is present, and the possible source of elevated calcium.
| Species | Canine, Feline |
|---|---|
| Patient Status | Acutely Ill, Suspected Cancer |
| Test | C-Reactive Protein (CRP), Haptoglobin (HPT), Neoplasia Index (NI), Parathyroid Hormone 1-84 (PTH), Thymidine Kinase type 1 (TK1), Total Calcium (tCa), Vitamin D (VitD) |
| Specimen Type | Serum (Frozen) |
| Fasting | Not Required |
